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  <xsd:element id="adag_OutsideMainlandOfChinaMember" name="OutsideMainlandOfChinaMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="adag_ConcentrationRiskSuppliersAxis" name="ConcentrationRiskSuppliersAxis" nillable="true" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="adag_ConcentrationRiskSuppliersDomain" name="ConcentrationRiskSuppliersDomain" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="adag_OneSupplierMember" name="OneSupplierMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element name="CollaborativeArrangementMilestonePaymentReceived" id="adag_CollaborativeArrangementMilestonePaymentReceived" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ExelixisIncAgreementMember" id="adag_ExelixisIncAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="CollaborativeArrangementUpfrontCashPaymentReceivable" id="adag_CollaborativeArrangementUpfrontCashPaymentReceivable" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="MilestonePaymentsReceivableDevelopmentAndRegulatoryMilestones" id="adag_MilestonePaymentsReceivableDevelopmentAndRegulatoryMilestones" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="MilestonePaymentsReceivableSalesBasedMilestones" id="adag_MilestonePaymentsReceivableSalesBasedMilestones" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="BorrowingsFromShanghaiPudongDevelopmentBankCo.Ltd.FourMember" id="adag_BorrowingsFromShanghaiPudongDevelopmentBankCo.Ltd.FourMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="GovernmentSubsidiesReceived" id="adag_GovernmentSubsidiesReceived" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="AdageneProjectC1Pte.Ltd.Member" id="adag_AdageneProjectC1Pte.Ltd.Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="GainLossOnSaleOfPropertyPlantEquipmentAndOperatingLeaseRightOfUseAsset" id="adag_GainLossOnSaleOfPropertyPlantEquipmentAndOperatingLeaseRightOfUseAsset" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="BorrowingsFromShanghaiPudongDevelopmentBankCo.Ltd.FiveMember" id="adag_BorrowingsFromShanghaiPudongDevelopmentBankCo.Ltd.FiveMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SanofiAgreementMember" id="adag_SanofiAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="InformationRelatedToOperatingLeasesTableTextBlock" id="adag_InformationRelatedToOperatingLeasesTableTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="InformationRelatedToOperatingLeaseActivityTableTextBlock" id="adag_InformationRelatedToOperatingLeaseActivityTableTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="OperatingLeaseRightOfUseAssetsAbstract" id="adag_OperatingLeaseRightOfUseAssetsAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="OperatingLeaseRentalExpenseAbstract" id="adag_OperatingLeaseRentalExpenseAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="InterestOfOperatingLeaseLiabilities" id="adag_InterestOfOperatingLeaseLiabilities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="OperatingLeaseRentalExpense" id="adag_OperatingLeaseRentalExpense" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="OperatingLeaseRightOfUseAssetAndInterestOfLeaseLiabilitiesAmortizationExpense" id="adag_OperatingLeaseRightOfUseAssetAndInterestOfLeaseLiabilitiesAmortizationExpense" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="WuxiBiologicsCaymanInc.Member" id="adag_WuxiBiologicsCaymanInc.Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ChinaConstructionBankCorporationMember" id="adag_ChinaConstructionBankCorporationMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ModificationOfVestingSchedulesAndConditionsOfShareOptionsMember" id="adag_ModificationOfVestingSchedulesAndConditionsOfShareOptionsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingFairValue" id="adag_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingFairValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="MilestoneAxis" id="adag_MilestoneAxis" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="MilestoneDomain" id="adag_MilestoneDomain" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="BorrowingsFromAgriculturalBankOfChinaLimitedOneMember" id="adag_BorrowingsFromAgriculturalBankOfChinaLimitedOneMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="BorrowingsFromAgriculturalBankOfChinaLimitedTwoMember" id="adag_BorrowingsFromAgriculturalBankOfChinaLimitedTwoMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="BorrowingsFromAgriculturalBankOfChinaLimitedThreeMember" id="adag_BorrowingsFromAgriculturalBankOfChinaLimitedThreeMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="BorrowingsFromBankOfJiangsuCo.LtdOneMember" id="adag_BorrowingsFromBankOfJiangsuCo.LtdOneMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="BorrowingsFromBankOfJiangsuCo.LtdTwoMember" id="adag_BorrowingsFromBankOfJiangsuCo.LtdTwoMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="CollaborativeArrangementUpfrontFeeReceived" id="adag_CollaborativeArrangementUpfrontFeeReceived" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="CollaborativeArrangementMilestoneFeeReceived" id="adag_CollaborativeArrangementMilestoneFeeReceived" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="CertainSeniorManagementPersonnelMember" id="adag_CertainSeniorManagementPersonnelMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="NoncashInvestmentIncome" id="adag_NoncashInvestmentIncome" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="OtherAccrualsAndLiabilitiesCurrent" id="adag_OtherAccrualsAndLiabilitiesCurrent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PerformanceBasedShareOptionsMember" id="adag_PerformanceBasedShareOptionsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="TimeBasedOptionsMember" id="adag_TimeBasedOptionsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PercentageOfShareBasedCompensationVestAnnually" id="adag_PercentageOfShareBasedCompensationVestAnnually" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="AtmOfferingMember" id="adag_AtmOfferingMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="StockCapitalReservedForFutureIssuance" id="adag_StockCapitalReservedForFutureIssuance" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsCancellationsInPeriod" id="adag_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsCancellationsInPeriod" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="SingleReportableSegmentMember" id="adag_SingleReportableSegmentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="DirectResearchAndDevelopmentExpenses" id="adag_DirectResearchAndDevelopmentExpenses" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="LabSuppliesAndOtherResearchAndDevelopmentExpenses" id="adag_LabSuppliesAndOtherResearchAndDevelopmentExpenses" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="IndirectResearchAndDevelopmentExpenses" id="adag_IndirectResearchAndDevelopmentExpenses" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="SecondSupplierMember" id="adag_SecondSupplierMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="MaximumStrategicInvestmentAmountToBeReceivedUnderSecuritiesAgreement" id="adag_MaximumStrategicInvestmentAmountToBeReceivedUnderSecuritiesAgreement" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="TemporaryEquityStockIssuedConvertedPriceValueDuringPeriodNewIssues" id="adag_TemporaryEquityStockIssuedConvertedPriceValueDuringPeriodNewIssues" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ChinaZheshangBankCo.LtdMember" id="adag_ChinaZheshangBankCo.LtdMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="WarrantsAndRightsNoteDisclosureTextBlock" id="adag_WarrantsAndRightsNoteDisclosureTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ClassOfWarrantOrRightWarrantsOutstandingRollForward" id="adag_ClassOfWarrantOrRightWarrantsOutstandingRollForward" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ClassOfWarrantOrRightExercisableNumber" id="adag_ClassOfWarrantOrRightExercisableNumber" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="ClassOfWarrantOrRightExercisePriceAbstract" id="adag_ClassOfWarrantOrRightExercisePriceAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ClassOfWarrantOrRightExercisableExercisePriceOfWarrantsOrRights" id="adag_ClassOfWarrantOrRightExercisableExercisePriceOfWarrantsOrRights" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ClassOfWarrantOrRightWeightedAverageRemainingLIfeAbstract" id="adag_ClassOfWarrantOrRightWeightedAverageRemainingLIfeAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ClassOfWarrantOrRightOutstandingWeightedAverageRemainingLife" id="adag_ClassOfWarrantOrRightOutstandingWeightedAverageRemainingLife" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ClassOfWarrantOrRightExercisableWeightedAverageRemainingLife" id="adag_ClassOfWarrantOrRightExercisableWeightedAverageRemainingLife" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="CollaborativeArrangementUpfrontCashPaymentRevenueRecognizedPercentage" id="adag_CollaborativeArrangementUpfrontCashPaymentRevenueRecognizedPercentage" type="xbrli:pureItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="TemporaryEquityTextBlock" id="adag_TemporaryEquityTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="TemporaryEquityDividendsPerShare" id="adag_TemporaryEquityDividendsPerShare" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="TemporaryEquityNumberOfSharesReceivableOnConversion" id="adag_TemporaryEquityNumberOfSharesReceivableOnConversion" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="TemporaryEquityMaximumOwnershipThresholdPostConversion" id="adag_TemporaryEquityMaximumOwnershipThresholdPostConversion" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="TemporaryEquityMaximumOwnershipThresholdHolderCanElectToReach" id="adag_TemporaryEquityMaximumOwnershipThresholdHolderCanElectToReach" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="TemporaryEquityMaximumNoticePeriodForIncreasingOwnershipLimit" id="adag_TemporaryEquityMaximumNoticePeriodForIncreasingOwnershipLimit" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="MilestonePaymentsReceivableDevelopmentAndCommercialBasedMilestone" id="adag_MilestonePaymentsReceivableDevelopmentAndCommercialBasedMilestone" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ThirdArcAgreementMember" id="adag_ThirdArcAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="UnderwrittenPublicOfferingMember" id="adag_UnderwrittenPublicOfferingMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SharesIssuedPricePerShareThresholdNumberOfDaysConsideredForVolumeWeightedAveragePrice" id="adag_SharesIssuedPricePerShareThresholdNumberOfDaysConsideredForVolumeWeightedAveragePrice" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PercentageOfShareholdingInterestRelatedParty" id="adag_PercentageOfShareholdingInterestRelatedParty" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="BorrowingsFromShanghaiPudongDevelopmentBankCo.Ltd.ThreeMember" id="adag_BorrowingsFromShanghaiPudongDevelopmentBankCo.Ltd.ThreeMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="BorrowingsFromShanghaiPudongDevelopmentBankCo.Ltd.OneMember" id="adag_BorrowingsFromShanghaiPudongDevelopmentBankCo.Ltd.OneMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ConjugateBioAgreementMember" id="adag_ConjugateBioAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
</xsd:schema>
